Hepatitis C, table 1, Hepatitis C Virus RNA Profilesin Chronically Infected Individuals: Do They Relate to DiseaseActivity? | Hepatitis Central

The latest research & treatment news about Hepatitis C infection, diagnosis, symptoms and treatment.

Menu Search

Hepatitis C Virus RNA Profiles in Chronically Infected Individuals: Do They Relate to Disease Activity?

Table  1.   Histological Features Observed in Chronic HCV Patients in Relation to Transaminase Profile and Viremia Levels

Minimal
Changes
Mild
CH
Moderate
CH
Severe
CH
P

ALT pattern over 12 months
  Normal ALT 3 15  5 0 .012
  Fluctuating 0 10 15 1
HCV-RNA fluctuations
  delta < 0.5 Log 3/3  3/15 3/12 0 NS
  delta greater than 0.5 Log 0 12/15 9/12 1/1

NOTE.   delta represents the difference between the maximum and minimum value of HCV RNA measured over time in each individual patient. 0.5 Log is considered the cut-off for the intrinsic variability of the assay.
Abbreviations: CH, chronic hepatitis; NS, not significant.

Return To Article

Table of Contents

Copyright © 1999 by the American Association for the Study of Liver Diseases.