Table 3. Features of Variant Syndromes Compared With Definite Autoimmune Hepatitis

table 3. Features of Variant Syndromes Compared With Definite Autoimmune Hepatitis

	AIH + PBC (n = 15)	AIH + PSC (n = 14)	Autoimmune Cholangitis (n = 11)	Definite AIH (n = 87)

Age (yr)	52 ± 4	42 ± 4	44 ± 3	44 ± 2
Men/women	2/13	5/9	2/9	12/75
AST (reference value, 31 U/L)	565 ± 159	232 ± 86	237 ± 122##	519 ± 38^,##
Bilirubin (reference value, 1.1 mg/dL)	6.4 ± 2	2.2 ± 0.5	2.8 ± 1.3	3.9 ± 0.5
Alkaline phosphatase (reference value, 309 U/L)	433 ± 68	843 ± 161^*	1045 ± 2442” alt=”” width=”5″ height=”10″ />	360 ± 26^*,
-Globulin (reference value, 0.7-1.7 g/dL)	3.3 ± 0.2	2.5 ± 0.3^**	1.74 ± 0.23	3.6 ± 0.1^,**
Immunoglobulin G (reference value, 700-1500 mg/dL)	2751 ± 222^§§§	2470 ± 330^¶¶	1596 ± 1954^§	3421 ± 132^{§,¶¶,§§§}
Immunoglobulin M (reference value, 60-300 mg/dL)	527 ± 107	232 ± 22	198 ± 30	278 ± 0.2
SMA ” alt=”” width=”9″ height=”12″ />1:40	10 (67)	6/13 (46)	5 (45)^§§	78 (90)^,§§,
ANA 1:40	10 (67)	6 (43)^***	10 (91)	66 (76)^***
DR4+	9 (60)	2 (14)	3/10 (30)	42 (48)
DR3+	5 (33)	10 (71)	4/10 (40)	43 (49)
Total score	14.5 ± 0.8	14.2 ± 1^¶	10.4 ± 0.9#	18.5 ± 0.2^,^¶,#

NOTE. Numbers in parentheses are percentages. Abbreviation: AIH, autoimmune hepatitis. Significantly different from each other at levels of ^,,,§^,, ¶^,#P < .0001, P = .0002, P = .0006, P = .0007, §§P = .001, ^,¶¶P = .006, ## ^,**^,P = .02, P = .03, and §§§P = .04.