Hepatitis C, Early Hepatocellular Carcinoma as an Entity With a High Rate of Surgical Cure, Current Information On Hepatitis C & treatments for the medical professional and patient.

Early Hepatocellular Carcinoma as an Entity With a High Rate of
Surgical Cure

table 3. Postsurgical Recurrence of HCC in 59 Patients

Profile	No. of Patients (%)		P
Profile	Early HCC Group With Recurrence (n = 12)	Overt HCC Group With Recurrence (n = 47)	P

Timing of recurrence			<.001
Early (<3 yr)	1 (8)	35 (74)
Late (3 yr)	11 (92)	12 (26)
Number of tumors			.27
Single	8 (67)	20 (43)
Two or three	3 (25)	15 (32)
Four or more	1 (8)	12 (25)
Mode of spread			.50
Local	0	4 (9)
Unilobar	8 (67)	25 (53)
Bilobar	4 (33)	18 (38)
Treatment for recurrence^*			.55
Second surgery	2 (17)	5 (11)
Ethanol injection	3 (25)	8 (17)
Arterial embolization	6 (50)	33 (70)
None	1 (8)	1 (2)
Median (range) duration (yr)
Time to recurrence	3.9 (2.1-11.9)	1.7 (0.2-7.9)	<.001
Survival after recurrence	2.3 (0.2-5.2)	2.4 (0.3-8.1)	.51

^* Selection of treatment depended on the pattern of recurrence and patient’s will. In seven patients who underwent a second surgery, a total of 12 tumors (18 ± 5 mm) resected were HCC of type-1 to -3 (n = 10) or type-early (n = 2). One patient in each group refused treatment.