Dropout Rate for Taking Sovaldi: 400% Higher Than Observed in Clinical Trials
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The Editors at Hepatitis Central
October 7, 2014
Learn about the financial impact for Hep C patients who are failing to complete their full, 12-week course of drug therapy with Sovaldi.
CVS: One In 12 Hepatitis C Patients Not Adhering To $1,000/Day Pill
By David Kroll, 9/17/14
Over 8 percent of hepatitis C patients taking Sovaldi (sofosbuvir; Gilead) are failing to complete their full, 12-week course of drug therapy, a dropout rate roughly four times that observed in clinical trials.
By discontinuing the drug, shown to have a 90+% cure rate, these patients (and their insurance providers) are incurring health care costs of $28,000 or $56,000, without knowing if they are rid of the virus.
Continue reading this entire article:
http://www.forbes.com/sites/davidkroll/2014/09/17/one-in-12-hepatitis-c-patients-not-adhering-to-1000day-pill/
10 Comments
i took sovaldi – was clear after week 4
continued to take the drug and was still clear after week 12
one month later i relapsed and my viral count was 8+ million
I just finished week 8, I really pray it takes.
Can you do it again?
How did you feel through it? I am getting more tired as time goes by:/
i doubt i can retake it – it is probably like Incivek (also relapsed) – and you can only do it once due to tolerance/resistance build-up (not the right word-i know)
i never felt bad at all – during any of my 4 treatments
i must have screwed up genetics – and i don’t respond well to interferon based treatments 🙁
I did six months on a trail,..geno 3a,…had huge viarl load when started,.5/6 ishtak,…and diabetic,…3 months post hep c free,…people need to take this for 4 months or more to have a good chance,…loads of insomnia and tiredness,..but my head was normal and i was determined,…Jerri have faith and Phil i,m sure there will be mix and match drugs in the next six months,..daclatisvir is now going thru so have faith!!…best of luck guys
I have to do 24 weeks (6 months) and I only have 5 more pills to take. I have been virus free since week 5 <12 and I am praying for no relapse.
Any one who intentionally drops out should have to do 48 weeks of interferon!
anyone please tell me in what condition should we have to stop treatment sovaldi/ribavirin/interferon????????????
Sovaldi and ribavirin taken together worked in 3 months is sufficient for Hepatis C. type 2 , 90 percent chance I won’t get the virus again without direct contact.
I did interferon plus Ribavirin last year, for 3-4 months. Didn’t kill the HepC but did screw up my thyroid such that I had to take meds for it. And was tired and listless This year I did Sovaldi, 180 days, plus Ribavirin, tired again and it still didn’t work. Finished the regimen of both those drugs, thyroid cleared, diabetes cleared, now I feel great but still have Hep C. This new drug is not for my genotype so I dunno what options might be available. Best of luck to all.
If you don’t take at least 12 weeks then your cheating yourself. I was cleared SVR since 4 weeks but stayed on for 24 weeks in a Gilead trial.
Praise God. I hope many more will be able to get the same results without a high price tag.