Drug-Related Fatality Stops Hepatitis C Trial
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Bristol-Myers Drops Hepatitis C Drug After Patient Death
Bloomberg News
By Ryan Flinn on August 24, 2012
Bristol-Myers Squibb Co. (BMY) has abandoned an experimental hepatitis C pill it bought for $2.5 billion earlier this year after one patient died and others were hospitalized while taking the drug in a study.
Bristol-Myers will take a charge of $1.8 billion in the third quarter related to research and development of the therapy, the New York-based company said in a regulatory filing today. The drugmaker suspended testing the medicine, known as BMS-986094, on Aug. 1 after a patient developed heart failure.
Bristol-Myers said yesterday it has discontinued development of the drug, part of a class of medicines called nucleotide polymerase inhibitors, and was consulting with U.S. regulators to assess the treatment’s effects. Along with the death, eight patients suffered from heart and kidney toxicity, the company said in a statement.
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6 Comments
i would rather die of heart failure than Hepatitis C. Been a Respiratory Therapist for 32 years; Seen both.
Why does it have to be one or the other? There has to be a treatment for Hep C that does not kill you or make you so sick you’d rather be dead. Read Andreas Moritz.
I have had hep c for over eleven years and after taking the rebetron and interferon, I never wanted to do it again…so I have spent the better part of my waking life keeping my immune system strong. I take a plant protein (not crazy about whey or too much soy) drink with “GREEN VIBRANCE” and flax seed oil. tumeric, and MSM (powder form), many vitamin supplements and other nutrients to feed my liver (NAC, milk thistle, dandelion root, alpha lipoic acid), and eat only “liver friendly” foods…Hot a book about what to do and what not to do….and that’s kept my levels strong….otherwise it’s symptoms and “meds” are going to haunt me….there is only our body that we can control….by what we put in it….good luck…
I concur. I’m fighting this battle for 5 years. Treatments have left me worse off than the Hep C virus. Waiting for a transplant and a cure. One that doesn’t kill me in spite of it.
I’ve tried the new meds(incivek)along with the standared treatment(Intrapheron/Rebatrol)and like helen after trying it the first time swore I would never EVER do that again!but along came incivek.Although it almost killed me or what seemed like death at the time I tried it,It’s been 5 mounths and I consider myself still in recovery but my follow up blood work shows normal liver function for the first time in many years,how long it will last is anybodys guess…good luck all!!
I finished the Incivek treatment. It shredded my intestinal track. I made it through with the help of pain pills. It gave me a peri- anal cyst that had to be cut out. I still have huge problems with my intestines , constantly going to the bathroom. Did any one else have this problem on Incivek? Or do I maybe have something else going on. I am cured though but those first 12 weeks were a real killer. I have had 3 treatments o Interferon, ribbaveron since 2003. Finally cured since 2011. I was first in my area to do the Incivek.