Hep C Trial with Sovaprevir Has 85% Success Rate
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Achillion hepatitis C drug shows promise in mid-stage study
Tue Aug 7, 2012 8:37pm EDT
(Reporting by Zeba Siddiqui in Bangalore; Editing by Anthony Kurian)
(Reuters) – Achillion Pharmaceuticals Inc said its experimental hepatitis C drug showed promising interim data in a mid-stage trial, sending its shares higher in extended trade.
The company said the drug sovaprevir, when given along with the standard therapy of pegylated interferon and ribavirin, showed no detectable virus level in a majority of patients four weeks after the end of the treatment period.
Of the 39 patients who received 12 weeks of additional standard therapy following 12 weeks of the combination therapy, a total of 33 patients in three different dosage arms showed sustained viral response a month later.
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15 Comments
85% and what are the long term side effects? Still not good enough.
What are the short and long term side effects?
when given along with the standard therapy of pegylated interferon and ribavirin. No Thanks !!
is genotype meter on this type of therapy?
Niiice! I did 11 months interferon/ribavirin and had to add procrit due to anemia. It’s been 4 years now and undetectable. Sure it was the toughest thing ever, but my energy is great! I no longer have brain fog! I ski, play tennis, and scuba. This new therapy for 12 weeks?? If it was me, I would do it in a heartbeat. I have quality of life at age 58. 🙂
I went through 24 weeks on and Abbott trial, with no interferon just ribavirin abt`450 abt`750 and Ritrovinal and have been virus free for almost 2 years. I never heard of any side effects and I felt great through the whole trial.
Can’t imagen why this is not in the news.
What Genotype?
Can u elaborate more on exactly what this is?
Ric, last month u stated it worked. Where did you go to get treated? sovaprevir not included? I guess the question is if we can get just the latter somewhere. Still winging it with brainfog and low energy.
Having done two rounds of pegylated interferon & ribavarin I have been told new treatments involving interferon & ribavarin could cause my liver to crash. Enough already, it’s time for new treatments.
85% results !!!! with which genotype?????
pharmassest and bristol meyers has a combo therapy 1 drug made by each company and no peg 100% cure rate and then pharmassest pulled out they were well into stage 2 trials.There is a petition going start by margarert dulley trying to convince pharmessest to do the right thing and resume these trials.Encourage all to sign and to spread the word for anyone affected to also sign
what genome?
Testing negative 4 weeks post treatment means nothing – take it out a year. If negative then, that is a positive outcome.
I don’t think any of the new drugs that come out that must be taken with interferon and ribaviran will really make a killing. The 2 newest ones seem to have a SVR rate over 85% for genotype 1’s so I think most will be waiting (if they can) for drugs to come out without using interferon which seems to be in about 2014-2015 hopefully. Whatever comes out will surely be “fast tracked”.