Human Cells in Mice Provide New Model for Studying HCV
Homo musculus: Researchers Create a “Humanized” Mouse for Liver Disease Studies
Long-awaited breakthroughs in developing preclinical animal models are signaling a new era for liver-targeted viruses and beyond
By Jessica Wapner October 21, 2010
Chronic infection with malaria and hepatitis B and C occurring in more than 800 million people worldwide leads to at least 1.5 million deaths yearly. Although significant strides have been made in treatment and vaccination for these liver-based diseases, shortfalls remain. Progress has been stymied for several reasons, chief among them is the lack of an effective research model. Now, advances in mouse model creation are conspiring to usher in a new era in the research and treatment of these life-threatening maladies, and possibly many others.
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