Human Cells in Mice Provide New Model for Studying HCV | Hepatitis Central

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Human Cells in Mice Provide New Model for Studying HCV

The Editors at Hepatitis Central
October 27, 2010

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By engineering mice livers to contain enough human cells, researchers at the Salk Institute for Biological Studies are making progress in the quest to find better therapeutic solutions for many ailments, including Hepatitis C.

Homo musculus: Researchers Create a “Humanized” Mouse for Liver Disease Studies

Long-awaited breakthroughs in developing preclinical animal models are signaling a new era for liver-targeted viruses and beyond

By Jessica Wapner October 21, 2010

Chronic infection with malaria and hepatitis B and C occurring in more than 800 million people worldwide leads to at least 1.5 million deaths yearly. Although significant strides have been made in treatment and vaccination for these liver-based diseases, shortfalls remain. Progress has been stymied for several reasons, chief among them is the lack of an effective research model. Now, advances in mouse model creation are conspiring to usher in a new era in the research and treatment of these life-threatening maladies, and possibly many others.

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http://www.scientificamerican.com/article.cfm?id=homo-musculus-researchers-create

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