New Herbal Compound Inhibits the Hepatitis C Virus
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With an estimated 150 million people chronically infected with the Hepatitis C virus, the stakes for developing a cure are high. In hopes of being first to defeat the Hepatitis C virus, most pharmaceutical companies have ignored the potential of herbal medicine. However, a presentation at the International Liver Congress in April 2014 put Chinese Herbal Medicine in the spotlight for having a chance of successfully treating Hepatitis C.
Evolved over thousands of years, Traditional Chinese Medicine (TCM) is a complete system of healthcare that includes a complex, highly evolved, therapeutic herbal component. In TCM theory, the Hepatitis C virus is traditionally considered to be a hot, toxic pathogen. As such, the Chinese Herbal Medicine treatment approach focuses on herbs known to clear heat and toxins. Although several Chinese herbal formulas have been used by TCM practitioners to help clients with Hepatitis C, the general population has not recognized the antiviral potential of Chinese herbs.
The European Association for the Study of the Liver (EASL) attracts the foremost hepatology experts as members and has an impressive track record in promoting research in liver disease, supporting education and promoting changes in liver health policy. At the April 2014 EASL meeting in London, Markus Peck-Radosavljevic, MD, Associate Professor of Medicine and Vice-Chairman at the Department of Gastroenterology and Hepatology at the Medizinische Universität Wien (MedUniWien) in Austria presented a study that a Chinese herbal extract demonstrated great potential for treating the Hepatitis C virus.
According to the Austrian researchers, SBEL1, a compound derived from a plant used in Chinese Herbal Medicine demonstrated activity against Hepatitis C viral replication in human liver cells. Based on their data:
- SBEL1 inhibited Hepatitis C activity at several different points in the virus’ lifecycle.
- SBEL1 was found to inhibit Hepatitis C activity by approximately 90 percent.
Unfortunately, the etiology of SBEL1 has not yet been revealed, except that it is a compound isolated from a Chinese herb:
- Found in certain regions of Taiwan and Southern China.
- Traditionally used to treat sore throats and inflammation.
In the Austrian study, scientists pre-treated human liver cells in vitro with SBEL1 prior to Hepatitis C infection. They found that SBEL1 pre-treated cells contained 23 percent less Hepatitis C protein than the control, suggesting that SBEL1 blocks virus entry. This indicates the herb contains a protective property. In addition:
- SBEL1 was also found to inhibit IRES-mediated translation, a critical process for Hepatitis C viral protein production.
- SBEL1 also impairs the viral RNA replication process.
As we hope for further research with this Chinese herbal constituent and eagerly await finding out what herb contains SBEL1, we are left with incomplete – yet encouraging news. Nonetheless, the capacity demonstrated by SBEL1 is on par with some of the most hopeful Hepatitis C drugs.
Finding out an herb that clears heat and toxins inhibits Hepatitis C viral replication in lab tests is not surprising to practitioners of TCM, but this research could be the beginning of greater acceptance of Chinese Herbal Medicine into the mainstream. Taking this information one step further, Peck-Radosavljevic’s poster may even convince a major pharmaceutical company to incorporate a potent herbal extract into an antiviral medication for a first-of-its-kind, integrative medicine Hepatitis C trial.
Related Articles
http://www.easl.eu/_about-easl, About EASL, Retrieved April 20, 2014, EASL, 2014.
http://www.hivandhepatitis.net/hepatitis-c/hepatitis-c-topics/hcv-treatment/438,632-hcv-alternative-complementary-therapy/4630-easl-2014-chinese-herbal-compound-inhibits-hepatitis-c-virus-replication, EASL 2014: Chinese Herbal Compound Inhibits Hepatitis C, Retrieved April 20, 2014, hivandhepatitis.com, 2014.
20 Comments
I contacted EASL, asking about the name of the herb and they could only refer me to the email address of a Dr. Lin who reported this study. Dr. Lin did not respond to my request for information on what herb or herbs constitutes SBEL1. I am afraid Big Pharma is obstructing any chance for its revelation and use.
Maybe it will help if more of us email Dr. Lin.
“The lead investigator of the study Mr Lin, may be able to help you further and he can be contacted at r01442016@ntu.edu.tw.”
Thanks for the info! Emailing him now.
I tried emailing Dr. Lin, however the email address shows as an invalid address.
It really is disgusting these greedy pharmaceutical companies want to keep these natural remedies all to themselves so they can profit from peoples sicknesses.
They will have to answer to God for this one day
After extensive research on this topic, the experienced Chinese herbalists seem to believe the SBEL1 compound is in the herbal remedy called YIN QIAO JIE DU PIAN
http://www.itmonline.org/arts/yinqiao.htm
http://www.amazon.com/Meridian-Classic-Teapills-Lonicera-Forsythia/dp/B00CBIF5QS/ref=sr_1_2?s=hpc&ie=UTF8&qid=1409423200&sr=1-2&keywords=YIN+QIAO+JIE+DU+PIAN
It could be Huang Qin or Andrographis, I am only guessing.
I studied herbs for a long time.
It is more beneficial and better, in so many ways to use a whole herb, than to isolate just one active compound and make it into medicine.
That is what Big Pharma will do to make more money.
Possible derived from oyster mushrooms Dr Lin did published study years back sounds similar
maybe it is a herb Rhodiola Kirilowii?
Interesting you would say that… I live in rural southern Oregon. I’ve been diagnosed with Hep C now for 5 years… and refuse interfeuron treatments. I am searching for alternatives now, since a year ago my numbers were extremely high, and I was encouraged to see a GI specialist.
Prior to being tested positive, I often hunted and consumed local, wild mushrooms, to my delight…. as mushrooms are one of my favorite foods. About a year ago, my roomate and I found a huge cache of oysters on a tree in the forest, and I made a big pot of soup.. cream of oyster mushroom… and it probably contained upwards of 5# of them, so highly concentrated. It made me really ill, or so I thought. Ill as in, gastrointestinal detox type symptoms. This year, I also made a soup from Bolete, and Matsutake mushrooms harvested in the forest and had a similar, but less intense reaction.
After being positive of the identification of these fungi, I did more research, and found that many experts suggest taking only a small amount of a newly found mushroom until you test your sensitivity.
Did you mean wild mushroom in the forest can help curing hep c?
I was responding to above poster’s comment about something helping that had oyster mushroom in it, which is wild here.
In times gone by, this discovery would have been heralded, not hidden and forbidden in a disgraceful manner by big pharma. Remember the amount of money riding on new drugs (cure). Big Pharma seems to have everyone in their pocket. The Chinese might blow the whistle here as they are very annoyed about the way the west (particularly the EU) has restricted the gift of Chinese herbal medicine with red tape.
goatgrass
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oxymatraine ? i think thats how u spell it ?
http://molpharm.aspetjournals.org/content/37/6/911.short
I would wager Huang Qin is it.
I have this herbal Taiwanese medicine for hepatitis c .If some one interested in buy reach me at samreen.ali30@yahoo.com
yes please. what cough mixture do you have
Taiwanese herbal medicine for complete cure of hepatitis B and C. It’s main ingredient in Taiwanese mushrooms. It’s Long being used in Taiwan for hepatitis c authentic cure and it’s also effective in cancer.
One course six bottles of small 80 tablets.which should be finished in twelve days by taking 40 tabs daily.
the failure of pharmaceutical is the mere isolation of the active compound, close but no cigars, pharmaceuticals will always fall short of the real thing!!!
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