Patient Enrollment Started in the Phase II HELIX-2 Clinical Trial | Hepatitis Central

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Patient Enrollment Started in the Phase II HELIX-2 Clinical Trial

The Editors at Hepatitis Central
December 4, 2013

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Learn more about samatasvir, simeprevir and TMC647055 – all of which are being tested for an all-oral, direct-acting antiviral (DAA) HCV combination therapy.

Idenix Pharma begins Phase II combination trial to treat hepatitis C virus infection

PBR Staff Writer

Published December 3, 2013

US-based biopharmaceutical company Idenix Pharmaceuticals has started patient enrollment in the Phase II HELIX-2 clinical trial evaluating an all-oral, direct-acting antiviral (DAA) HCV combination therapy of samatasvir, simeprevir and TMC647055 for the treatment of hepatitis c virus (HCV) infection.

Samatasvir is a once-daily pan-genotypic NS5A inhibitor of Idenix; simeprevir is a once-daily NS3/4A protease inhibitor jointly developed by Janssen R&D Ireland and Medivir; while TMC647055 is a once-daily NS5B non-nucleoside polymerase inhibitor boosted with low-dose ritonavir developed by Janssen.

Continue reading this entire article:
http://clinicaltrials.pharmaceutical-business-review.com/news/idenix-pharma-begins-phase-ii-combination-trial-to-treat-hepatitis-c-virus-infection-031213-4139779

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