Study Announcement for Advanced Cancer and Liver Dysfunction | Hepatitis Central

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Study Announcement for Advanced Cancer and Liver Dysfunction

The Editors at Hepatitis Central
November 10, 2006

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Western medicine has typically had little to offer those with end stage liver disease, which can be marked by advanced cancer and irregular liver function. In the following press release, you will learn more about a recently announced Phase 1 study examining the effects an experimental drug has on this serious combination of conditions.

Summary: PHI-50 NCI#6432: A Phase I Pharmacokinetic Study of PS-341 in Patients with Advanced Malignancies and Varying Degrees of Liver Dysfunction for the CTEP-Sponsored Organ Dysfunction Working Group

You have been asked to participate in this research study because you have advanced cancer that is no longer responding to standard treatment and your liver function is normal or is no longer normal. The purpose of this research study is to find out the highest dose of an experimental drug PS-341 that can be given to subjects with advanced cancer and abnormal liver function without causing unmanageable side effects. Additionally, researchers will be looking to find out how the study drug moves through the body.

Patient Inclusion/Exclusion Criteria:

– See http://clinicaltrials.coh.org for additional information.

Contact:

City of Hope National Medical Center
1500 East Duarte Road
Duarte, CA 91010-3000
Telephone: 866-896-HOPE (4673)
Source: www.centerwatch.com

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